In this Cornell Research article, the work of Peng Chen is highlighted for his discoveries in metal regulation in relation to the cell and how its function can be both preventive and therapeutic.
“Chen’s research has led to discoveries of first-of-their-kind mechanisms of Cu/Zn-responsive transcriptional regulation, but new questions have also emerged," the article says. "He is further determining the mechanism that couples CueR/ZntR regulation to DNA mechanical tension and the mechanism of Zur’s biphasic unbinding kinetics from DNA, two novel phenomena.”
Takumi Matsuzawa/Provided
Membraneless organelles known as “condensates” form and disappear every day to help organize the biochemistry in our cells. This image captures in vitro condensates dissolving after a specific chemical is injected from the right. The color represents the concentration of the protein that makes up the condensates.
