Unusual Metal Regulation—Single-Cell, Single-Molecule Levels

In this Cornell Research article, the work of Peng Chen is highlighted for his discoveries in metal regulation in relation to the cell and how its function can be both preventive and therapeutic.

“Chen’s research has led to discoveries of first-of-their-kind mechanisms of Cu/Zn-responsive transcriptional regulation, but new questions have also emerged," the article says. "He is further determining the mechanism that couples CueR/ZntR regulation to DNA mechanical tension and the mechanism of Zur’s biphasic unbinding kinetics from DNA, two novel phenomena.”

Read the entire article here.