Professor of Chemistry and Chemical Biology David B Collum's lab recently received a $2.79 million grant from the National Institutes of Health to fund his research on alkali metals reactivity and selectivity. These metals play a vital role in academic and industiral laboratories' development of medical compounds.
Collum's lab emphasizes the role of non-covalent auxiliaries and focusing on two subsets of alkali metal chemistry that have proven virtually impenetrable to careful scrutiny: lithium enolates and sodium amides. The studies are focused on non-covalent auxiliaries—stoichiometrically formed mixed aggregates of lithium enolates and catalytically active triamines in organosodium chemistry.
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Cornell chemists have found a way to encapsulate a molecule’s quantum mechanical information so they can feed that – rather than simpler structural information – into ML algorithms, providing up to 100 times more accuracy than the current most popular method