Liu studies the bone morphogenetic protein (BMP) signaling pathway, which plays critical roles in multiple developmental and homeostatic processes. Malfunction of this pathway can cause various disorders, including cardiovascular diseases and cancer.
Provided
This cartoon illustrates how RNA polymerase generates torsional stress in DNA during transcription. Chromatin, composed of nucleosomes with DNA wrapped around histone proteins, buffers this stress, enabling the polymerase to transcribe through nucleosomes.
Ryan Young/Cornell University
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