Research Focus
Research in the Lambert group is focused in the area of catalysis. We are especially interested in the development of novel catalytic strategies for selective organic synthesis. Projects that we have been active in include electrophotocatalysis, catalytic carbonyl-olefin metathesis, and the study of aromatic ions. In approaching these and other problems, we strive to develop highly effective practical solutions while asking interesting questions of reactivity and mechanism. We bring both synthetic and physical organic techniques to bear on answering these questions as we work to develop catalyst systems of practical value for the field of organic synthesis.
Publications
- Cross-Coupling of Amines via Photocatalytic Denitrogenation of In Situ-Generated Diazenes. Steiniger, K. A.; Lamb, M. C.; Lambert, T. H. J. Am. Chem. Soc. 2023, 145, 11524-11529.
- Olefination of Carbonyls with Alkenes Enabled by Electrophotocatalytic Generation of Distonic Radical Cations. Steiniger, K. A.; Lambert, T. H. Science Adv. 2023, 9, eadg3026.
- Electrophotocatalytic Oxygenation of Multiple Contiguous Adjacent C–H Bonds. Shen, T.; Li, Y.-L.; Ye, K.-Y.; Lambert, T. H. Nature 2023, 614, 275-280.
- Ring-opening Metathesis Polymerization Using Hydrazonium Initiators. Quach, P.; Hsu, J. H.; Keresztes, I.; Fors, B. P.; Lambert, T. H. Angew. Chem. Int. Ed. 2022, 61, e202203344.
- Electrophotocatalytic Diamination of Vicinal C–H Bonds. Science 2021, 371, 620-626.
- Reductive Electrophotocatalysis: Merging Electricity and Light to Achieve Extreme Reduction Potentials. Kim, H.; Kim, H.; Lambert, T. H.; Lin, S. J. Am. Chem. Soc. 2020, 142, 2087-2092.
- Electrophotocatalysis with a Trisaminocyclopropenium Radical Dication. Huang, H.; Strater, Z. M.; Rauch, M.; Shee, J.; Sisto, T. J.; Nuckolls, C.; Lambert, T. H. Angew. Chem. Int. Ed. 2019, 58, 13318-13322.
- An Aromatic Ion Platform for Enantioselective Brønsted Acid Catalysis. Gheewala, C. D.; Collins, B. E.; Lambert, T. H. Science 2016, 351, 961-965.
In the news
- Researchers win grants to remove carbon from air, manufacturing
- Meshri family funds Baker 200 restoration project
- Two chemistry professors win Cope Scholar Award
- Klarman Fellow: Capturing carbon with future-focused chemistry
- A&S honors 23 faculty with endowed professorships
- From methane to microbes: 2030 Project conveys first grants
- Chemistry professor helped catalyze Nobel-winning breakthrough
- $2M in New Frontier Grants boost high-impact A&S research
