Overview
Dr. Martin Graef is an Assistant Professor in the Department of Molecular Biology and Genetics and a member of the Graduate Field of Genetics, Genomics and Development and the Graduate Field of Biochemistry, Molecular and Cell Biology. The Graef lab studies the molecular mechanisms and physiological functions of autophagy and cellular ageing with links to human disease. They focus on the interplay of autophagy with lipid and membrane biology, mitochondria behavior and function, and genome maintenance. To address these fundamental questions, the Graef lab uses biochemistry, state-of-the-art live cell imaging, and system-wide genetics and proteomics approaches towards building quantitative models for yeast and mammalian cells.
